At Point Nemo, the closest people are usually in orbit
This map is centered on Point Nemo and drawn so that distance from the center is true to scale in every direction — the two rings below are the same rings you'd draw with a compass on a globe.
Point Nemo is the spot in the ocean farthest from any land — the "oceanic pole of inaccessibility." The nearest inhabited land is roughly 2,688 km away, days by boat. But the International Space Station orbits only about 408 km up, and its path regularly crosses directly overhead.
Those are two different kinds of distance — one along the Earth's surface, one straight up — which isn't a fair apples-to-apples comparison. It's shown to scale here anyway, because that's exactly what makes it stick: for a person standing at Point Nemo, the closest fellow humans are, quite often, six astronauts moving at 28,000 km/h a few hundred kilometers overhead.